Ogni anno, in Europa le malattie cardiovascolari sono responsabili di oltre quattro milioni di decessi. L’aumento di C-LDL è una causa prevalente di atherosclerotic cardiovascular disease e, parimenti, la riduzione degli eventi cardiovascolari correla linearmente con la riduzione dei livelli di colesterolo LDL, senza una soglia inferiore (almeno fino a 35 mg/dl)
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