La mononucleosi è una malattia infettiva causata dal virus Epstein-Barr (EBV) della famiglia herpes virus. Non ha una stagionalità ben precisa e neanche una platea delineata. Colpisce grandi e piccoli, in ogni angolo del mondo, e ha un decorso che va dai 30 ai 45 giorni. Si viene infettati dallo scambio di saliva – da qui il nome “malattia del bacio” – o dal contatto con oggetti precedentemente toccati da una persona già infetta.
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